Group and history

History :

MMBM is a large multidisciplinary team of about 30 persons, dedicated to the application of physics and chemistry to biology and medicine. The first streamline of research is dedicated to fundamental biophysics studies of molecular interactions and molecular transport. This comprises in particular DNA-protein interactions, cell-cell interactions, molecular motors. These processes and properties are studied at the single object (single molecule, single cell) level. The group is also specialized in the development of original instrumentation for biophysical studies, in particular original single-molecule nanomanipulation tools. Another research streamline of the group is the development of bioanalytical methods and tools, based on innovations in physics, chemistry, soft matter and microfluidics. The group has specialized in lab-on-chips and microfluidics, being the second in France in size, for this topic. Research in this domain involves both the development of new generic enabling technologies, and that of integrated instruments dedicated to specific biomedical applications. One of our aims is to push development as far as possible towards clinical practical use, thanks to the priviledged clinical environment of Curie Institute. For this purpose, the group is also strongly involved in translational medicine, industrial cooperation and technology transfer. The spirit and strengths of the group will be better exemplified by a selection of its current projects.

Manpower :

Senior staff scientists : 4 Student : 18 Postdoc : 7 Technician : 2 Unit Joint facilities : 2

Members :

Jean-Louis Viovy
Research director 1st class
CNRS
Tel.: +33 (0)1 56 24 67 52
Fax: +33 (0)1 40 51 06 36

Group leader : Macromolecules and microsystems in biology and medicine (MMBM)

Giovanni Cappello
Research Scientist 1st class
CNRS
Tel.: +33 (0)1 56 24 64 68
Fax: +33 (0)1 40 51 06 36

Single molecule, molecular motors and homologous recombination

Giuliana Carzedda
Assistant engineer
Institut Curie
Tel.: +33 (0)1 56 24 64 68
Fax: +33 (0)1 40 51 06 36

At Institut Curie since August 2006, in charge of the group administration. Co-organizer of the…

Nelly Henry
Research Scientist 1st class
CNRS
Tel.: +33 (0)1 56 24 64 95
Fax: +33 (0)1 40 51 06 36

Current research : Colloids for cell biophysics : T-cell activation and mechanics - Bacterial…

Laurent Malaquin
Research Scientist 2nd class
CNRS
Tel.: +33 (0)1 56 24 68 45
Fax: +33 (0)1 40 51 06 36

Research Scientist 2nd class ( since 2007) at Institut Curie. Post Doc at LPN-CNRS, Marcoussis -…

Anaïs Ali Cherif
Doctorant
University
Tel.: +33 (0)1 56 24 64 65
Fax: +33 (0)1 40 51 06 36

Traitements de surfaces, récepteurs olfactifs, microfluidique

Scott Atwell
PhD student
Institut Curie
Tel.: +33 (0)1 56 24 64 68
Fax: +33 (0)1 40 51 06 36

Study of homologous recombination on single molecule

Virginie Audonnet
Postdoctorant
Institut Curie
Tel.: +33 (0)1 56 24 67 70
Fax: +33 (0)1 40 51 06 36

PhD "Bio-functionalization of surfaces, micro and nanoparticles for lab-on-chips", defense on…

Julien Autebert
PhD student
University
Tel.: +33 (0)1 56 24 67 68
Fax: +33 (0)1 40 51 06 36

Préparation de la thèse: « Laboratoire sur puce pour la séparation et…

Stefano Begolo
Doctorant
Tel.: +33 (0)1 56 24 64 69
Fax: +33 (0)1 40 51 06 36

Miniaturisation, microfluidique en goutte, détection d'ADN

Nadège Bois
Doctorant
University
Tel.: +33 (0)1 56 24 64 68
Fax: +33 (0)1 40 51 06 36

Molecular analysis of single cell, Alzheimer's disease, microfluidique.

Nadia Bourouina
Doctorant
University
Tel.: +33 (0)1 56 24 64 63
Fax: +33 (0)1 40 51 06 36

Colloïdes liquides pour l'ingénierie cellulaire

François-Damien Delapierre
Doctorant
University
Tel.: +33 (0)1 56 24 68 15
Fax: +33 (0)1 40 51 06 36

Auto-assemblage, nanoparticules, microfluidique

Morgan Delarue
Master student
University
Tel.: +33 (0)1 56 24 64 69
Fax: +33 (0)1 40 51 06 36

"I am a master 2 student in an internship regarding the growth of metastasis, and more precisely…

Mohamed Diakité
Doctorant
Tel.: +33 (0)1 56 24 64 80
Fax: +33 (0)1 40 51 06 36

Microfluidique, Micro-Nanofabrication

Ludovic Disseau
Doctorant
University
Tel.: +33 (0)1 56 24 67 68
Fax: +33 (0)1 40 51 06 36

Etude des interactions entre l'ADN et Rad51 lors de la recombinaison homologue, à l'échelle de la…

Fahima Faqir
Ingénieur biologiste
Institut Curie
Tel.: +33 (0)1 56 24 64 94
Fax: +33 (0)1 40 51 06 36

Master 2 Compétence Complémentaire Informatique (2004)Master 1 de Biologie…

Francesca Farina
Doctorant
Institut Curie
Tel.: +33 (0)1 56 24 64 65
Fax: +33 (0)1 40 51 06 36

2000-2005 Università degli Studi di Milano (degree in Physics) 2006-2007 Solvay Solexis,…

Olivier Galy
Doctorant
University
Tel.: +33 (0)1 56 24 64 76
Fax: +33 (0)1 40 51 06 36

Microrhéologie, physique des biofilms bactériens

Jing Geng
Postdoctorant
Institut Curie
Tel.: +33 (0)1 56 24 64 76
Fax: +33 (0)1 40 51 06 36

Surface attached cell response to stress, Biofilm biopysics

Sabine Grosser
Master student
University
Tel.: +33 (0)1 56 24 64 95
Fax: +33 (0)1 40 51 06 36

Julien Husson
Postdoctorant
Tel.: +33 (0)1 56 24 67 75
Fax: +33 (0)1 40 51 06 36

2008- : Institut Curie, Paris, France, post-doc with Nelly Henry, J.-L. Viovy's group, study of…

Alisha Lussiez
Student
University
Fax: +33 (0)1 40 51 06 36

John Manzi
Assistant engineer
Institut Curie
Tel.: +33 (0)1 56 24 67 47
Fax: +33 (0)1 40 51 06 36

2008 - : Assistant Ingénieur - PhysicoChimie, UMR 168, Institut Curie 2007 - 2007: Lab…

Sandrine Miserere
Postdoctorant
Tel.: +33 (0)1 56 24 68 44
Fax: +33 (0)1 40 51 06 36

PhD "Development of a polymer microfluidic system for DNA analysis", defense on 14/12/2009

Reza Mohamadi
Postdoctorant
Tel.: +33 (0)1 56 24 67 68
Fax: +33 (0)1 40 51 06 36

Postdoctoral Researcher in Institut Curie from October 2007, Postdoctoral Researcher, Nagoya…

Fabien Montel
Postdoctorant
Institut Curie
Tel.: +33 (0)1 56 24 64 69
Fax: +33 (0)1 40 51 06 36

2008 : PostDoc Institut Curie : Measuring pressure develloped by a growing tumoral tissue using a…

Guillaume Mottet
Postdoctorant
Institut Curie
Tel.: +33 (0)1 56 24 64 65
Fax: +33 (0)1 40 51 06 36

Post-Doctorant à l'Institut Curie : projet de qPCR sur puce et développement de…

Karla Perez-Toralla
Doctorant
University
Tel.: +33 (0)1 56 24 64 69
Fax: +33 (0)1 40 51 06 36

2009-2012 : Doctorat Physique/Biologie : « Fabrication d'un système microfluidique…

Benoît Rogez
Trainee
University
Tel.: +33 (0)1 56 24 64 68
Fax: +33 (0)1 40 51 06 36

Up to the end of July 2010: Internship on the tracking of single DNA molecules in vivo, at the…

Sanae Tabnaoui
Doctorant
University
Tel.: +33 (0)1 56 24 68 15
Fax: +33 (0)1 40 51 06 36

Micro fluidic total analysis system for the early diagnostic of neurodegenerative disorders

Vélan Taniga
Technical engineer
Institut Curie
Tel.: +33 (0)1 56 24 64 76
Fax: +33 (0)1 40 51 06 36

Development of a lab-on-chip for nosocomial infections diagnostic, microfluidic chips design, COC…

Maeva Vignes
Doctorant
University
Tel.: +33 (0)1 56 24 64 80
Fax: +33 (0)1 40 51 06 36

As a training chemist in the ENS Lyon, I first meet Amyloïd Bêta (implicated in…