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Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors

Uracil processing by SMUG1 in the absence of UNG triggers homologous recombination and selectively kills BRCA1/2-deficient tumors

1 mars 2025Molecular Cell

DOI : 10.1016/j.molcel.2025.01.031

Auteurs

Daniele Musiani, Hatice Yücel, Marie Vallette, Annapaola Angrisani, Rania El Botty, Bérengère Ouine, Niccolo Schintu, Caroline Adams, Manon Chevalier, Derrien Heloise, Ahmed El Marjou, Ivan Nemazanyy, Marie Regairaz, Elisabetta Marangoni, Daniele Fachinetti, Raphael Ceccaldi